Using the MM5 mesoscale model coupled with the cloud parameters scheme developed by Chinese Academy of Meteorological Sciences,this paper simulated a typical convective-stratiform mixed cloud precipitation process affected by Typhoon “Utor” in southern Hunan Province on August 13, 2013. The spatial and temporal characteristics of cloud microphysical structure during this weather process and the optimal timing and location of artificial precipitation enhancement were analyzed. The results show that the variation trends of various hydrometeors mixing ratio with  time were basically the same, which presented single peak type distribution, and the peak values appeared around 14:00 on August 13. During the whole development process of the cloud system, the horizontal distributions of all kinds of hydrometeors were uneven, and the distribution of cumulus clouds appeared obvious blocky. With the development of the cloud system, the larger value areas of hydrometeors ratio mixing existed a clear westward movement trend. At the maturity stage of cloud system, the meridional distribution range of cloud water was not large (about 60 km), and all kinds of hydrometeors coincided well in the vertical direction. Supercooled water existed in clouds which developed strongly in the vertical direction. The distribution of rainwater corresponded well with that of graupel, which indicated that the melting of graupel was the main source of rainwater during this process. The 450 hPa was the most favorable height for cloud seeding in the early stage of mixed convective-stratiform cloud development.